Reproduction Abstracts

PI3K is a family of enzyme involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3K-Akt signaling pathway negatively is regulated by PTEN. Recently, we developed the method for activation of dormant follicles by using in vitro culture of ovarian fragments treated with PTEN inhibitor and PI3K activator (IVA, in vitro activation). We applied this approach to infertility treatm...